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What is psoriasis?

Psoriasis is a chronic inflammatory condition that primarily affects the skin, but it can also impact the nails and occasionally the joints. It manifests as red, scaly plaques on the skin that are often covered with dry, white scales.

These plaques can appear anywhere on the body, with the scalp being a common area for thick, noticeable patches. The condition can cause significant emotional distress due to its chronic nature and its potential to be exacerbated by illness or stress.

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Symptoms of psoriasis

The most common symptoms of psoriasis include:

  • Red plaques: These are areas of inflammation and thickening of the skin, often covered with dry, white scales.
  • Scalp involvement: Psoriasis on the scalp can be particularly severe, leading to thick, flaky patches.
  • Nail changes: Psoriasis can cause various nail abnormalities, including pitting (small dents or depressions), onycholysis (lifting of the nail from the nail bed), and changes in nail color.
  • Joint issues: In some cases, psoriasis can be associated with psoriatic arthritis, which causes joint pain, stiffness, and swelling.
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Causes of psoriasis

The exact cause of psoriasis is not fully understood, but it is believed to be related to an immune system malfunction.

In psoriasis, the immune system mistakenly attacks healthy skin cells, leading to rapid skin cell turnover. This accelerated cell growth results in the formation of plaques on the skin.

While the precise triggers are not known, certain factors are thought to contribute to the onset or worsening of the condition:

  • Genetic predisposition: A family history of psoriasis increases the likelihood of developing the condition.
  • Immune system dysfunction: Psoriasis is considered an autoimmune disease, where the immune system erroneously targets normal skin cells.
  • Environmental factors: Stress, infections, injuries, and certain medications can trigger or exacerbate psoriasis.
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Treatments for psoriasis

Treatment for psoriasis varies based on the severity of the condition and whether it involves joint symptoms. Options include:

  • Topical therapies: These are creams or ointments applied directly to the skin to reduce inflammation and slow down skin cell growth. Common topical treatments include corticosteroids, vitamin D analogs, and tar preparations.
  • Phototherapy: This treatment involves exposing the skin to controlled amounts of ultraviolet light, which can help slow the growth of skin cells and reduce inflammation.
  • Oral medications: Systemic medications, taken by mouth, are used for more severe cases of psoriasis. These may include methotrexate, cyclosporine, or acitretin, which work by suppressing the immune system or altering skin cell production.
  • Biologics: These are advanced medications administered via injection or infusion that target specific parts of the immune system involved in psoriasis. They are typically used for moderate to severe cases and are prescribed when other treatments have not been effective.

Managing psoriasis often requires a combination of treatments and ongoing care to control symptoms and improve quality of life. It's important for individuals with psoriasis to work closely with their dermatologist to find the most effective treatment plan for their specific needs.

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